Derivatization reagents for GC, silylation, TMCS

A 1 molar solution of TMCS in methanol is suited for the esterification of free carboxylic acids and transesterification of glycerides. TMCS and silyl ether remove water and thus drive the reaction to completion. These products contain harmful substances which must be specially labeled as hazardous.

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Technical Data

Selling unit 6×50 mL, 20×1 mL
Method Gas chromatography (GC), derivatization
Composition Trimethylchlorosilane (TMCS)
Derivatization type Silylation
Recommended application(s) Derivatization, Esterification of free carboxylic acids, TMCS and silyl ether remove water, Transesterification of glycerides
Storage temperature 2–8 °C / 36–46 °F
Hazardous material Yes
Safety Information according to CLP
DANGER
H225 Highly flammable liquid and vapour.H301 Toxic if swallowed.H312 Harmful in contact with skin.H314 Causes severe skin burns and eye damage.H331 Toxic if inhaled.
P260sh Do not breathe dust/vapours. P264 Wash hands thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P280sh Wear protective gloves/eye protection. P301+310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. P303+361+353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower]. P305+351+338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P330 Rinse mouth. P405 Store locked up. P501 Dispose of contents/container to regulated waste treatment.

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