HPTLC/TLC glass plates, silica layer with chiral selector, CHIRALPLATE, 10×20 cm

CHIRALPLATE – Special layer for TLC enantiomer separation. Separation based on ligand exchange, i. e. formation of ternary mixed-ligand complexes with Cu(II) ions. Differences in the stability of the diastereomeric complexes cause chromatographic separation. Available as glass plates with fluorescent indicator. A review on the application of CHIRALPLATE has been given by K. Günther [J. Chromatogr. 448 (1988) 11–30].

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Technical Data

Hazardous material No
Method Thin layer chromatography (HPTLC/TLC)
Phase CHIRALPLATE
Base material Glass plates coated with impregnated silica gel
Surface chemistry Silica gel impregnated with Cu(II) ions and a chiral selector (proline derivative)
Mode Reversed phase (RP) with ligand exchange
Plate size 10×20 cm
Layer thickness 0.25 mm
Layer hardness Standard, soft
UV indicator Yes
Support material / backing Glass
Particle size Not available or not applicable
Particle type Fully porous particles (FPP)
Particle shape Irregular
Pore size Not available or not applicable
Pore volume Not available or not applicable
Binder Yes
pH stability 2.0–8.0
Recommended application(s) Amino acids, Dipeptides, Enantiomers, Lactones, N-formylamino acids, N-methylamino acids, Thiazolidine derivatives, α-alkylamino acids, α-hydroxycarboxylic acids
Temperature stability High
Storage temperature RT
Scope of delivery 25x TLC glass plates (10×20 cm)

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